NEAH has identified a comprehensive list of neglected livestock diseases for which mAbs and rAbs to important immune cell markers as well as specific for various pathogens affecting food animals that can be used to guide rationale veterinary vaccine R&D.
Research
Explore Our Resource Guide
Livestock Species and Diseases
| Disease | Goats | Sheep | Cattle | Poultry | Pigs | Gap / Unmet Need |
|---|---|---|---|---|---|---|
| African Swine Fever | ✓ | no highly effective vaccines | ||||
| Animal African Trypanosomiasis | ✓ | ✓ | ✓ | ✓ | no vaccines | |
| Avian influenza (highly pathogenic) | current vaccines do not prevent disease transmission | |||||
| Brucellosis | ✓ | ✓ | ✓ | ✓ | live vaccines for cattle and goats | |
| Contagious bovine pleuropneumonia | ✓ | live vaccines have limitations | ||||
| Contagious caprine pleuropneumonia | ✓ | bacterin vaccines have limitations | ||||
| East Coast Fever | ✓ | Muguga cocktail vaccine has limitations | ||||
| Foot-and-mouth disease | ✓ | ✓ | ✓ | ✓ | improved vaccines needed | |
| Fowlpox | ✓ | vaccines confer poor protection against virulent field strains | ||||
| Goatpox | ✓ | live vaccines are generally effective; DIVA vaccines needed | ||||
| Mareks Disease | ✓ | vaccines reduce clinical disease, but do not prevent persistent infection and shedding | ||||
| Peste des Petits Ruminants | ✓ | ✓ | Existing live vaccines are good; thermotolerant, DIVA vaccines needed | |||
| Porcine Cysticercosis | ✓ | TSOL18 vaccine-oxfendazole combination highly effective | ||||
| Q Fever (Coxiellosis) | ✓ | ✓ | inactivated vaccine only for cattle; safety issues; DIVA vaccine needed | |||
| Rift Valley Fever | ✓ | ✓ | ✓ | live and inactivated current vaccines have shortcoming; DIVA-compatible RVF vaccines with better safety and efficacy are needed | ||
| Sheep Pox | ✓ | live vaccines are generally effective; DIVA vaccines needed | ||||
| Virulent Newcastle Disease | ✓ | vaccines prevent mortality/morbidity; lack of genotype-matched vaccines that reduce disease transmission | ||||
| Zoonotic tuberculosis | ✓ | ✓ | no vaccines |
International Organizations involved in food animal health and well-being:
- African Union InterAfrican Bureau for Animal Resources
- Biotechnology and Biological Sciences Research Council (BBSRC)
- Boehringer Ingelheim Veterinary Public Health
- Centers for Disease Control and Prevention – One Health Basics
- Ceva Santé Animale
- Explore Animal Health
- The Global Alliance for Livestock Veterinary Medicines (GALVMed)
- Health for Animals
- International Development Research Centre (IDRC)
- International Livestock Research Institute
- International Union of Immunological Societies
- International Veterinary Vaccinology Network (IVVN )
- MSD Animal Health
- National Resource Council – Critical Role of Animal Science Research in Food Security and Sustainability
- One Health Commission
- Scottish Government Farming and Rural Affairs
- Supporting Evidence-Based Interventions (SEBI)
- The Immunological Toolbox
- UK Department for Environment, Food & Rural Affairs (DEFRA)
- Unicef – The State of Food Security and Nutrition 2023
- Virbac
- World Health Organization
- World Organization for Animal Health (Formally OIE)
- Zoetis Center for Transboundary and Emerging Diseases
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